Scientific Studies on Kratom

Please click on the links for more information in regards to Kratom academic research.

Assessment of Kratom under the CSA Eight Factors and Scheduling Recommendation submitted to the DEA by Pinney & Associates 11-16

Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators, Journal Of The American Chemical Society: 6-6-16 Report

Pharmacokinetics of Mitragynine in Man: 12-21-14

Alkaloids Identified in Mitragyna Speciosa, Kratom: 10-8-2014

Kratom and Other Mitragynines: The Chemistry and Pharmacology of Opiods from a Non-Opium Source: 2015

An Evidence-Based Systematic Review of Kratom: 6-3-2013

Total Synthesis of (-)-Mitragynine and Analogues :2012

Evaluation of Antioxidant and Antibacterial Activities of Aqueous, Methanolic and Alkaloid Extracts from Mitragyna Speciosa (Rubiaceae Family) Leaves: 2009


Self-treatment of opioid withdrawal using kratom (Mitragynia speciosa korth): 2008

Acute Toxicity Study of Standardized Mitragyna speciosa Korth Aqueous Extract in Sprague Dawley Rats:​


In Vitro and in Vivo Effects of Three Different Mitragyna speciosa Korth Leaf Extracts on Phase II Drug Metabolizing Enzymes—Glutathione Transferases (GSTs):

The Neuromuscular Blockade Produced by Pure Alkaloid, Mitragynine and Methanol Extract of Kratom Leaves (Mitragyna speciosa Korth.):

Genes Induced by High Concentration of Salicylic Acid in Mitragyna Speciosa: